Miriam H. Morales, PhD.

Understanding the contribution of neurons and astrocytes to the neuronal circuitry underlying brain functions

Control of neuronal excitability by activating ion channels with magnetic fields
Control of astrocytic calcium signaling by activation ion channels with magnetic fields

Areas of Research

01

Neuromodulation

Developing experimental tools to manipulate neuron and astrocyte activity with high spatial and temporal resolution

02

Magnetogenetics

Developing tools that use noninvasive magnetic fields to activate ion channels enabling the control of cell activity

03

Synaptic Transmission

Developing tools to independently control pre and postsynaptic activity

04

Astrocytes function as integrative processors in the brain.

Investigating the role of intracellular calcium signaling in astrocytes as the mechanism for integrating and transmitting information within the brain

05

Role of Astrocytes in Behavior

Investigating the contribution of astrocytes to brain functions, such as behavior

06

Astrocytes as Cargo Cells to Treat Brain Diseases

Bioengineering astrocytes as therapeutic cellular agents to treat brain diseases

Publications

Selected publications

  1. Electrophysiological Mechanisms and Validation of Ferritin-Based Magnetogenetics for Remote Control of Neurons. Journal of Neuroscience (2024)
  2. Evaluating methods and protocols of ferritin-based magnetogenetics. Iscience (2021)
  3. Lipid oxidation induced by RF waves and mediated by ferritin iron causes activation of ferritin-tagged ion channels. Cell Reports (2020)
  4. Temperature-activated ion channels in neural crest cells confer maternal fever–associated birth defects. Science Signaling (2017)

Current Position

Research Scientist

  • University of California, Berkeley

    Helen Wills Neuroscience Institute and Electrical Engineering and Computer Science

    Li Ka Shing Center, 1951 Oxford Street, Berkeley, CA 94720, USA